130080-39-6

Basic information

• Product Name: Thiazole, 2-fluoro-5-nitro- (9CI)
• Synonyms: Thiazole, 2-fluoro-5-nitro- (9CI)
• CAS NO: 130080-39-6
• Molecular Formula: C3HFN2O2S
• Molecular Weight: 148.1156432
• Product Categories: HALIDE
• Mol File: 130080-39-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Thiazole, 2-fluoro-5-nitro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Thiazole, 2-fluoro-5-nitro- (9CI)(130080-39-6)
• EPA Substance Registry System: Thiazole, 2-fluoro-5-nitro- (9CI)(130080-39-6)

Safety Data

• Hazardous Substances Data: 130080-39-6(Hazardous Substances Data)

Upstream product

• 121-66-4 2-amino-5-nitro-1,3-thiazole 

Relevant articles and documents

Facile direct conversion of aminoheterocycles to fluoro-heterocycles using t-butylthionitrite or t-butylthionitrate with sodium tetrafluoroborate

Amino-nucleic acids and amino-heterocycles reacted readily with t-butylthionitrite or t-butylthionitrate in the presence of anhydrous sodium tetrafluoroborate in neutral and aprotic media to afford the corresponding fluoro-nucleic acids and fluoroheterocycles respectively in good yields.

ORGANIC SYNTHESIS USING ORGANOSULFUR-NITRITES AND -NITRATES

Thionitrites or thionitrates have been considered to be unstable.However, bulky groups' thio-NOn such as t-butylthio-nitrites and -nitrates have been readily synthesized and found to be stable enough for the use of the useful organic syntheses as an excellent nitrosation and diazotization reagents under mild conditions.Direct conversion of amines to the corresponding halides in the presence of copper halides (II), fluorination of heterocyclic amines in the presence of sodium tetrafluoroborate, α- oximation of methylene groups in ketones, facile cleavage of C=N bond to ketones, and desulfurization of thioacetals and thioketals, and other useful organic syntheses are described.