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CAS

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130351-65-4

1-[3-deoxy-3-(hydroxymethyl)-beta-D-lyxofuranosyl]pyrimidine-2,4(1H,3H)-dione is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 130351-65-4 Structure

  • Basic information

    1. Product Name: 1-[3-deoxy-3-(hydroxymethyl)-beta-D-lyxofuranosyl]pyrimidine-2,4(1H,3H)-dione
    2. Synonyms: 1-(3-Deoxy-3-C-(hydroxymethyl)-beta-D-lyxo-pentofuranosyl)uracil; 1-[3-Deoxy-3-C-(hydroxymethyl)-.beta.-D-lyxo-pentofuranosyl]uracil; 2,4(1H,3H)-Pyrimidinedione, 1-(3-deoxy-3-(hydroxymethyl)-beta-D-lyxofuranosyl)-; 2,4(1H,3H)-Pyrimidinedione, 1-[3-deoxy-3-(hydroxymethyl)-.beta.-D-lyxofuranosyl]-
    3. CAS NO:130351-65-4
    4. Molecular Formula: C10H14N2O6
    5. Molecular Weight: 258.228
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 130351-65-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: 1.542g/cm3
    6. Refractive Index: 1.601
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-[3-deoxy-3-(hydroxymethyl)-beta-D-lyxofuranosyl]pyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-[3-deoxy-3-(hydroxymethyl)-beta-D-lyxofuranosyl]pyrimidine-2,4(1H,3H)-dione(130351-65-4)
    11. EPA Substance Registry System: 1-[3-deoxy-3-(hydroxymethyl)-beta-D-lyxofuranosyl]pyrimidine-2,4(1H,3H)-dione(130351-65-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 130351-65-4(Hazardous Substances Data)

130351-65-4 Usage

Type of Compound

Nucleoside analogue

Function

Antiviral agent

Structure

Resembles thymidine, a nucleoside essential for DNA replication

Mechanism of Action

Inhibits the activity of reverse transcriptase enzyme

Target Viruses

HIV and other retroviruses

Effect on Virus Replication

Prevents the virus from replicating and spreading within the body

Role in Treatment

Key component in the treatment of HIV and AIDS

Usage

Commonly used in combination with other antiretroviral drugs to manage the progression of the disease

Check Digit Verification of cas no

The CAS Registry Mumber 130351-65-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,3,5 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 130351-65:
(8*1)+(7*3)+(6*0)+(5*3)+(4*5)+(3*1)+(2*6)+(1*5)=84
84 % 10 = 4
So 130351-65-4 is a valid CAS Registry Number.

130351-65-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[(2R,3S,4R,5S)-3-hydroxy-4,5-bis(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

1.2 Other means of identification

Product number -
Other names 3'-Hydroxymethyl Lyxo U

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:130351-65-4 SDS

130351-65-4Relevant articles and documents

Synthesis of antiviral activity of 3'-deoxy-3'-C-hydroxymethyl nucleosides

Bamford,Coe,Walker

, p. 2494 - 2501 (2007/10/02)

A series of 3'-branched-chain sugar nucleosides, in particular 3'-deoxy-3'-C-hydroxymethyl nucleosides, have been synthesized and evaluated as antiviral agents. Reaction of 1-(2,3-epoxy-5-O-trityl-β-D-lyxo-pentafuranosyl) derivatives 12 and 13, of uracil

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