Synthesis of N-arylhydroxylamines by Pd-catalyzed coupling
Pd-catalyzed coupling of aryl halides with TeocNHOTBS, followed by treatment of the products with TBAF, provides effective access to a wide range of N-arylhydroxylamines by a route that produces stable doubly-protected intermediates and allows the protective groups to be removed under mild conditions that do not cause extensive degradation of the final product.
Beaudoin, Daniel,Wuest, James D.
p. 2221 - 2223
(2011/05/05)
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