130445-52-2

Basic information

• Product Name: IM 24
• Synonyms: IM 24
• CAS NO: 130445-52-2
• Molecular Formula: C15H19ClN2O
• Molecular Weight: 278.77716
• Mol File: 130445-52-2.mol

Chemical Properties

• Boiling Point: 384.1°Cat760mmHg
• Flash Point: 186.1°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 4.2E-06mmHg at 25°C
• CAS DataBase Reference: IM 24(CAS DataBase Reference)
• NIST Chemistry Reference: IM 24(130445-52-2)
• EPA Substance Registry System: IM 24(130445-52-2)

Safety Data

• Hazardous Substances Data: 130445-52-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H18N2O.ClH/c1-5-8-16(2)11-13-9-12-10-14(18-4)6-7-15(12)17(13)3;/h1,6-7,9-10H,8,11H2,2-4H3;1H

Upstream product

• 130445-56-6 C-(5-Methoxy-1-methyl-1H-indol-2-yl)-methylamine 
• 106-96-7 propargyl bromide 

Relevant articles and documents

Acetylenic and allenic derivatives of 2-(5-methoxyindolyl)methylamine: synthesis and evaluation as selective inhibitors of the monoamine oxidases A and B

A series of acetylenic and allenic derivatives of 2-(5-methoxyindolyl)methylamine has been synthesized.The new compounds were studied as inhibitors of the A and B forms of the mitochondrial monoamine oxidase (MAO) from bovine brain, using (14)C-tyramine as the substrate and clorgyline and l-deprenyl as references.All the studied compounds were MAO inhibitors.However, these compounds either did not show selectivity (compounds 3a-3d, 4c, 4e, 4m and 4o) or they were selective for MAO-A (compounds 4a, 4b, 4d, 4f-4l, 4n and 4p).Some of the compounds showed a similar inhibitory potency for MAO-A and lower for MAO-B than clorgyline and the higher selectivity for MAO-A was about 2.5 times that of clorgyline.Selectivity was shown only by acetylenic and allenic potent inhibitors, but no simple relationship between inhibitory potency and selectivity was found.