13045-88-0Relevant articles and documents
Regio- And Stereoselective Carboindation of Internal Alkynyl Ethers with Organosilicon or -stannane Nucleophiles
Kang, Kyoungmin,Nishimoto, Yoshihiro,Yasuda, Makoto
, p. 13345 - 13363 (2019/11/16)
We achieved regio- and stereoselective carboindation of terminal and internal alkynyl ethers using InI3 and organosilicon or -stannane nucleophiles to synthesize (Z)-β-alkoxyalkenylindiums. The carbometalation regio- and stereoselectively proce
Scope and limitations of the intermolecular furan-yne cyclization
Zeiler, Anna,Ziegler, Michael J.,Rudolph, Matthias,Rominger, Frank,Hashmi, A. Stephen K.
supporting information, p. 1507 - 1514 (2015/08/04)
Different types of alkynes were reacted with 2,5-disubstituted furans in order to evaluate the scope of the intermolecular furan-yne reaction. With ethynyl aryl ethers as starting materials, 2-phenoxy phenols were accessible in moderate to good yields. A different reaction mode was observed for alkynes bearing electron-withdrawing substituents. For these starting materials a cis-selective hydroarylation took place in an anti-Markovnikov fashion in excellent yields. 1,2-Diynes turned out to be suitable starting materials as well. Due to the second alkynyl moiety, after an initial phenol synthesis, a subsequent hydro-alkoxylation by the newly formed phenolic oxygen gives access to benzofurans in a tandem process.
