Study of the reaction between cyanohydrins and chlorosulfonyl isocyanate. A new, efficient method for the one-pot synthesis of 2,4-oxazolidinediones
The reaction between cyanohydrins and chlorosulfonyl isocyanate, followed by acid hydrolysis, provides and efficient route for the one-pot preparation of 5,5-disubstituted 2,4-oxazolidinediones.
A facile one-pot synthesis of 3-unsubstituted-2,4-oxazolidinediones via in situ generation of carbamates from α-hydroxyesters using trichloroacetyl isocyanate
A convenient, high yield one-pot methodology for the synthesis of pharmaceutically interesting 3-unsubstituted-2,4-oxazolidinediones from α-hydroxyesters is described. A primary carbamate was generated in situ from the corresponding α-hydroxyester and tri