Synthesis of benzo[3,4-h][1,6]naphthyridines via Friedlaender condensation with active methylenes
Novel 4-amino-6-chloroquinoline-3-carbaldehyde has been synthesized by synchronous reduction by lithium aluminiumhydride and finally oxidation with MnO2. Friedlaender condensation of it with reactive methylenes furnished novel benzo[3,4-h][1,6]