130754-18-6

Basic information

• Product Name: Benzeneacetonitrile, alpha,4-difluoro- (9CI)
• Synonyms: Benzeneacetonitrile, alpha,4-difluoro- (9CI)
• CAS NO: 130754-18-6
• Molecular Formula: C₈H₅F₂N
• Molecular Weight: 153.1288064
• Product Categories: HALIDE
• Mol File: 130754-18-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzeneacetonitrile, alpha,4-difluoro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetonitrile, alpha,4-difluoro- (9CI)(130754-18-6)
• EPA Substance Registry System: Benzeneacetonitrile, alpha,4-difluoro- (9CI)(130754-18-6)

Safety Data

• Hazardous Substances Data: 130754-18-6(Hazardous Substances Data)

Upstream product

• 459-22-3 4-fluorophenylacetonitrile 
• 140-29-4 phenylacetonitrile 

Relevant articles and documents

Selective electrolytic fluorinations in 70% HF/30% pyridine

The selective fluorination of compounds containing benzylic hydrogen atoms was accomplished by electrolysis in a mixture of 70% HF and 30% pyridine (Olah's reagent) using a square wave alternating current (1.76-2.75 V, 0.02-0.05 Hz) and Pt electrodes. This method can be used in the laboratory to prepare conveniently gram-size quantities of monofluorinated products. An ion radical mechanism has been proposed.

ELECTRFLUORATION EN POSITION BENZYLIQUE DANS LE SULFOLANE

The use of sulfolane as a solvent instead of acetonitrile in the electrofluorination of benzylic derivatives 1, (R=H, Cl) gives greater yields of benzylic fluorides 2, since the formation of acetamide byproducts 4 is prevented.However, the parallel fluorination of the aromatic nucleus is not avoided under these conditions.