An efficient pyrrole synthesis via silaphenylmercuric triflate catalyzed cyclization of homopropargyl azides
A mixture of phenylmercuric acetate and trifluoromethanesulfonic acid or silica gel supported phenylmercuric tri-fluoromethanesulfonate (silaphenyl mercuric triflate) efficiently catalyzed the formation of pyrroles from homopropargyl azide derivatives. The reactions proceed using 20 mol% of the heterogeneous catalyst with yields of isolated pyrroles ranging from 74% to 99%. Georg Thieme Verlag Stuttgart · New York.
Highly enantioselective partial hydrogenation of simple pyrroles: A facile access to chiral 1-pyrrolines
A highly enantioselective Pd-catalyzed partial hydrogenation of simple 2,5-disubstituted pyrroles with a Bronsted acid as an activator has been successfully developed, providing chiral 2,5-disubstituted 1-pyrrolines with up to 92% ee.