- METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID
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In this method, an oligonucleotide is prepared by using, as a synthesis unit, a novel nucleoside monomer compound represented by formula (I) [wherein X, R1, Y, Base, Z, Ar, R2, R3 and n are each as defined in Claim 1]. The
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Paragraph 0142; 0143; 0144
(2015/11/16)
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- RNA synthesis via dimer and trimer phosphoramidite block coupling
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The solid-phase synthesis of oligoribonucleotides using dimer and trimer phosphoramidite blocks is described. This method significantly reduces the total number of steps required in the synthesis of a target RNA sequence, provides more material, and simpl
- Hassler, Matthew,Wu, Yi Qiao,Mallikarjuna Reddy,Chan, Tak Hang,Damha, Masad J.
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p. 2575 - 2578
(2011/06/21)
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