131042-61-0Relevant articles and documents
Design and Synthesis of Highly Potent and Specific ABHD6 Inhibitors
Malamas, Michael S.,Lamani, Manjunath,Farah, Shrouq I.,Mohammad, Khadijah A.,Miyabe, Christina Yume,Rajarshi, Girija,Wu, Simiao,Zvonok, Nikolai,Chandrashekhar, Honrao,Wood, JodiAnne,Makriyannis, Alexandros
supporting information, (2021/09/08)
Fine-tuning than complete disruption of 2-arachidonoylglycerol (2-AG) metabolism in the brain represents a promising pharmacological approach to limit potential untoward effects associated with complete blockade of monoacylglycerol lipase (MGL), the prima
Synthesis and CLOGP correlation of imidooxy anticonvulsants
Farrar,Ciechanowicz-Rutkowska,Grochowski,Serda,Pilati,Filippini,Hinko,El-Assadi,Moore,Edafiogho,Andrews,Cory,Nicholson,Scott
, p. 3517 - 3525 (2007/10/02)
Continuing structure-activity studies on the anticonvulsant activity of analogs of N-(benzyloxy)-2-azaspiro[4.4]nonane-1,3-dione (2a), which displayed anti-electroshock seizure (MES) activity and a protective index (TD50/ED50) of >4.5 are reported. An in-
Synthesis and Anticonvulsant Activity of Imidooxy Derivatives
Edafiogho, Ivan O.,Scott, K. R.,Moore, Jacqueline A.,Farrar, Vida A.,Nicholson, Jesse M.
, p. 387 - 392 (2007/10/02)
Previous results of anticonvulsant activity in several imidooxy carboxylates related to (aminooxy)acetic acid in young chicks, prompted an in-depth reinvestigation of these analogues in mice.A series of 22 succinimidooxy, phthalimidooxy, and naphthalimido