131052-43-2

Basic information

• Product Name: 1-(3-FURYL)METHANAMINE HYDROCHLORIDE
• Synonyms: 3-AMINOMETHYLFURAN HYDROCHLORIDE;3-FURYLMETHYLAMINE HYDROCHLORIDE;1-(3-FURYL)METHANAMINE HYDROCHLORIDE;1-(3-Furyl)methaneamineHCl;1-(3-Furyl)methaneaminehydrochloride;3-(AMINOMETHYL)FURAN HCL;(Fur-3-yl)methylamine hydrochloride;1-(Furan-3-yl)MethanaMine HCl
• CAS NO: 131052-43-2
• Molecular Formula: C5H8ClNO
• Molecular Weight: 133.58
• Mol File: 131052-43-2.mol

Chemical Properties

• Melting Point: 187-191
• Boiling Point: 136.4°Cat760mmHg
• Flash Point: 36.3°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 7.39mmHg at 25°C
• CAS DataBase Reference: 1-(3-FURYL)METHANAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-FURYL)METHANAMINE HYDROCHLORIDE(131052-43-2)
• EPA Substance Registry System: 1-(3-FURYL)METHANAMINE HYDROCHLORIDE(131052-43-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 131052-43-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
1-(3-FURYL)METHANAMINE HYDROCHLORIDE is used as a building block for the synthesis of various compounds with potential biological activities. Its unique structure allows for the creation of new molecules that can target specific biological pathways or receptors, contributing to the discovery of novel therapeutic agents.
Used in Organic Synthesis:
1-(3-FURYL)METHANAMINE HYDROCHLORIDE is used as a reagent in organic synthesis, facilitating the formation of complex organic molecules. Its presence in reactions can lead to the production of a wide range of chemical products, expanding the scope of organic chemistry.
Used in the Production of Functionalized Amines and Heterocycles:
1-(3-FURYL)METHANAMINE HYDROCHLORIDE serves as a precursor for the production of other functionalized amines and heterocycles. These compounds are essential in various chemical and pharmaceutical applications, including the development of new drugs and the synthesis of advanced materials.
Used in Therapeutic Applications:
Due to its unique chemical structure and potential medicinal properties, 1-(3-FURYL)METHANAMINE HYDROCHLORIDE has the potential to be used in various therapeutic applications. Its ability to interact with biological systems may lead to the development of new treatments for a range of diseases and conditions.

InChI:InChI=1/C5H7NO.ClH/c6-3-5-1-2-7-4-5;/h1-2,4H,3,6H2;1H

Relevant articles and documents

Quinazoline derivatives possessing anti-tumor activity

The invention relates to quinazoline derivatives, or pharmaceutically-acceptable salts thereof, which possess anti-tumor activity; to processes for their manufacture; and to pharmaceutical compositions containing them. The invention provides a quinazoline of the formula: STR1 wherein R1 is hydrogen or amino, or alkyl or alkoxy each of up to 6 carbon atoms; or R1 is substituted alkyl or alkoxy each of up to 3 carbon atoms; R2 is hydrogen, alkyl, alkenyl, alkynyl, hydroxyalkyl, halogenoalkyl or cyanoalkyl each of up to 6 carbon atoms; Ar is phenylene or heterocyclene; L is a group of the formula --CO.NH--, --NH.CO--, --CO.NR3 --, --NR3. CO--, --CH=CH--, --CH2 O--, --OCH2, --CH2 S--, --SCH2 --, --CO.CH2 --, --CH2.CO-- or --CO.O--, wherein R3 is alkyl of up to 6 carbon atoms; and Y is aryl or heteroaryl or a hydrogenated derivative thereof: or Y is a group of the formula --A--Y1 in which A is alkylene, cycloalkylene, alkenylene or alkynylene each of up to 6 carbon atoms and Y1 is aryl or heteroaryl or a hydrogenated derivative thereof; or a pharmaceutically-acceptable salt thereof.