Synthesis of α-CN and α-CF3 N-heterocycles through tandem nucleophilic additions
Using a readily available secondary aminoalkyne as starting material, a powerful strategy was discovered to prepare precursors of biologically important unnatural cyclic aminoacids and fluorinated N-heterocycles with important ring sizes (e.g., 5-7) in a
Han, Junbin,Xu, Bo,Hammond, Gerald B.
p. 3450 - 3453
(2011/08/07)
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