Discovery of a series of imidazo[4,5-b ]pyridines with dual activity at angiotensin II Type 1 receptor and peroxisome proliferator-activated receptor-γ
Mining of an in-house collection of angiotensin II type 1 receptor antagonists to identify compounds with activity at the peroxisome proliferator-activated receptor-γ (PPARγ) revealed a new series of imidazo[4,5-b]pyridines 2 possessing activity at these
Casimiro-Garcia, Agustin,Filzen, Gary F.,Flynn, Declan,Bigge, Christopher F.,Chen, Jing,Davis, Jo Ann,Dudley, Danette A.,Edmunds, Jeremy J.,Esmaeil, Nadia,Geyer, Andrew,Heemstra, Ronald J.,Jalaie, Mehran,Ohren, Jeffrey F.,Ostroski, Robert,Ellis, Teresa,Schaum, Robert P.,Stoner, Chad
p. 4219 - 4233
(2011/08/22)
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