Structure-activity relationship of 2-hydroxy-2-aryl-2,3-dihydro-imidazo[1, 2-a]pyrimidinium salts and 2N-substituted 4(5)-aryl-2-amino-1H-imidazoles as inhibitors of biofilm formation by Salmonella Typhimurium and Pseudomonas aeruginosa
A library of 80 1-substituted 2-hydroxy-2-aryl-2,3-dihydro-imidazo[1,2-a] pyrimidinium salts and 54 2N-substituted 4(5)-aryl-2-amino-1H-imidazoles was synthesized and tested for the antagonistic effect against biofilm formation by Salmonella Typhimurium a
Steenackers, Hans P.L.,Ermolat'Ev, Denis S.,Savaliya, Bharat,Weerdt, Ami De,Coster, David De,Shah, Anamik,Van Der Eycken, Erik V.,De Vos, Dirk E.,Vanderleyden, Jozef,De Keersmaecker, Sigrid C.J.
experimental part
p. 3462 - 3473
(2011/07/09)
COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS
This invention relates to substituted 2-aminoimidazoles and their imidazo[1,2- a]pyrimidinium salts precursors being active against biofilm formation. The present invention also relates to antimicrobial compositions comprising a microbial biofilm formatio
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Page/Page column 29
(2011/07/30)
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