- Synthesis and chiral separation of some antitumor agents
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Four Z-isomers of 1,1-dichloro-2,2,3-triarylcyclopropane (DTACs), designed as potent antitumor agents, were synthesized from their appropriately substituted ethenes, which were prepared from the Grignard reaction followed by the dehydration of their inter
- Singh, Satendra,Meyer, Karen L.,Magarian, Robert A.
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- Synthesis and Biological Evaluation of a Series of 1,1-Dichloro-2,2,3-triarylcyclopropanes as Pure Antiestrogens
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A series of 1,1,-dichloro-2,2,3-triarylcyclopropanes (DTACs) was synthesized and evaluated as pure antiestrogens.Addition of 4-methoxy- or 4-(benzyloxy)phenyl Grignard reagents to p-methoxy, p-benzyloxy, or unsubstituted deoxybenzoins, followed by dehydra
- Day, Billy W.,Magarian, Robert A.,Jain, Pramod T.,Pento, J. Thomas,Mousissian, Gorgin K.,Meyer, Karen L.
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p. 842 - 851
(2007/10/02)
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