Efficient synthesis of nucleoside aryloxy phosphoramidate prodrugs utilizing benzyloxycarbonyl protection
An efficient method for the synthesis of nucleoside phosphoramidates prodrugs (6a-f) has been developed that employs a simple protection/deprotection sequence of the nucleoside with benzyloxycarbonyl (Cbz). The coupling reaction of Cbz-protected derivativ
Cho, Jong Hyun,Amblard, Franck,Coats, Steven J.,Schinazi, Raymond F.
experimental part
p. 5487 - 5493
(2011/08/06)
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