- Heterocycle-substituted styryl-4-phenylpyridine derivative as well as preparation method and medical application thereof
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The invention relates to a heterocycle-substituted styryl-4-phenylpyridine derivative, a preparation method thereof and an application of the heterocycle-substituted styryl-4-phenylpyridine derivativeas a PD-1/PD-L1 inhibitor. Specifically, the invention discloses a compound shown as a formula (I) or pharmaceutically acceptable salt, stereoisomer, solvate or prodrug thereof, and a preparation method and application thereof, and the definition of each group in the formula is shown in the specification and claims in detail.
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Paragraph 0140-0142
(2020/11/02)
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- HETEROARYL SUBSTITUTED HETEROCYCLYL SULFONES
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The invention relates to aryl substituted heterocyclyl sulfones as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
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Page/Page column 60
(2015/11/09)
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- NOVEL TRPV3 MODULATORS
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Disclosed herein are modulators of TRPV3 of Formula (I) (I) wherein p is 1, 2, 3, or 4, and G1, X1, X2, X3, X 4, X5, G2, Z1, Ra, Rb, and u are as defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also presented.
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Paragraph 1657; 1658
(2013/05/21)
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- 2- (TERT - BUTOXY) -2- (7 -METHYLQUINOLIN- 6 - YL) ACETIC ACID DERIVATIVES FOR TREATING AIDS
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The invention provides compounds and salts thereof as d herein. The invention also provides pharmaceutical compositions comprising a compound disclosed herein, processes for preparing compounds disclosed herein, intermediates useful for preparing compound
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Page/Page column 108
(2013/07/19)
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