2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
Compounds are disclosed having the formulae: STR1 wherein R1 is selected from the group, consisting of radicals represented by the general formulae: STR2 wherein Y is selected from the group consisting of lower alkyl, lower alkoxy, and halogen;
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(2008/06/13)
2-Aralkoxyadenosines: Potent and Selective Agonists at the Coronary Artery A2 Adenosine Receptor
A Langendorff guines pig heart preparation served for the assay of agonist potency of a series of 26 2-aralkoxyadenosines at the A1 and A2 receptors of, respectively, the atrioventricular node (conduction block) and coronary arteries
Ueeda, Masayuki,Thompson, Robert D.,Arroyo, Luis H.,Olsson, Ray A.
p. 1340 - 1344
(2007/10/02)
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