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CAS

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132125-31-6

5'-isocyano-2',5'-dideoxyuridine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 132125-31-6 Structure

  • Basic information

    1. Product Name: 5'-isocyano-2',5'-dideoxyuridine
    2. Synonyms: 5'-isocyano-2',5'-dideoxyuridine
    3. CAS NO:132125-31-6
    4. Molecular Formula: C10H11 N3 O4
    5. Molecular Weight: 237.22
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 132125-31-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: °Cat760mmHg
    3. Flash Point: °C
    4. Appearance: /
    5. Density: g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5'-isocyano-2',5'-dideoxyuridine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5'-isocyano-2',5'-dideoxyuridine(132125-31-6)
    11. EPA Substance Registry System: 5'-isocyano-2',5'-dideoxyuridine(132125-31-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 132125-31-6(Hazardous Substances Data)

132125-31-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 132125-31-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,1,2 and 5 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 132125-31:
(8*1)+(7*3)+(6*2)+(5*1)+(4*2)+(3*5)+(2*3)+(1*1)=76
76 % 10 = 6
So 132125-31-6 is a valid CAS Registry Number.

132125-31-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[(2R,4S,5R)-4-hydroxy-5-(isocyanomethyl)oxolan-2-yl]pyrimidine-2,4-dione

1.2 Other means of identification

Product number -
Other names 5'-Isocyano-2',5'-dideoxyuridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:132125-31-6 SDS

132125-31-6Downstream Products

132125-31-6Relevant articles and documents

Synthesis and antiretrovirus properties of 5'-isocyano-5'-deoxythymidine, 5'-isocyano-2',5'-dideoxyuridine, 3'-azido-5'-isocyano-3',5'-dideoxythymidine, and 3'-azido-5'-isocyano-2',3',5'-trideoxyuridine

Hiebl, Johann,Zbiral, Erich,Balzarini, Jan,Clercq, Erik De

, p. 1426 - 1430 (2007/10/02)

The 5'-azidonucleosides 3 and 4 were obtained by treating thymidine and 2'-deoxyuridine with TPP/DEAD/HN3.The 3'-O-silylated 5'-azido-5'-deoxythymidine 5 and the corresponding 2'-deoxyuridine derivative 6 were transformed to the formamides (7 and 8, respectively) and dehydrated to the protected 5'-isocyano derivatives 9 and 10; deblocking gave 5'-isocyano-5'-deoxythymidine (11) and 5'-isocyano-2',5'-dideoxyuridine (12). 2,3'-anhydro-5'-formamido derivatives of thymidine and 2'-deoxyuridine (19 and 20, respectively) were prepared by three different ways.In the most direct synthesis 3 and 4 were transformed to the 2,3'-anhydro-5'-azidonucleosides 17 and 18 by using TPP/DEAD; following the reaction with TPP/HCO2COCH3 gave 19 and 20.Nucleophilic opening reaction with LiN3 yielded the 3'-azido-5'-formylamino derivatives 21 and 22.Dehydration to 3'-azido-5'-isocyano-3',5'-dideoxythymidine (23) and 3'-azido-5'-isocyano-2',3',5'-trideoxyuridine (24) was achieved with tosyl chloride/pyridine.In contrast with 3'-azido-3'-deoxythymidine, compounds 11, 12, 23 and 24 were devoid of any marked inhibitory effect against DNA and RNA viruses including human immunodeficiency virus type I (HIV).

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