- Synthesis and Evaluation of Surface and Biological Properties of Some Lactic Acid-Based Anionic Surfactants
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In the present study, 11 lactic acid-based anionic surfactants were synthesized and evaluated for their surface and biological activities. The synthesis involved the esterification of lactic acid with a range of fatty alcohols differing in chain length as well as in branching and unsaturation. The resultant ester was sulfonated by treatment with chlorosulfonic acid followed by salt formation with aqueous NaOH solution. The surface properties of all the synthesized surfactants were determined using surface tensiometry. Synthesized surfactants showed low critical micelle concentration (CMC) values and a decreasing trend with an increase in the alkyl chain length. Alkyl branching also led to a mild change in CMC values when compared with linear counterparts having the same number of carbon atoms, though such decreases or increases were observed to be dependent on the position and number of the branching. Some of the synthesized surfactants exhibited good antimicrobial and anti-cancer activities against the tested microbial strains and cell lines.
- Sathyam Reddy, Yasa,Sujitha, Pombala,Kumar, Chityal Ganesh,Kanjilal, Sanjit,Vijayalakshmi, Penumarthy
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- SKIN EXTERNAL PREPARATIONS AND COSMETICS
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An object of the present invention is to provide skin external preparations and cosmetics which contain a branched acyl carnitine and have excellent formulation stability. A skin external preparation of the present invention includes a carnitine derivative represented by the following Formula (1) and/or a carnitine derivative salt represented by the following Formula (2), and an amphoteric surfactant. In Formula (1), R1 and R2 are each independently a C1-18 optionally branched, saturated or unsaturated aliphatic hydrocarbon group. In Formula (2), R1 and R2 are the same as in Formula (1), X? is a specific anion and Y+ is a specific cation.
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- Ultraviolet resistant sunscreen compositions
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A sunscreen composition for leaving a protective film on skin, comprising a UVB light absorbing sunscreen, a polymer vehicle, an oil-soluble solubilizer, and alkoxylated castor oil as an emulsifier. The protective film has an aggregate cohesive energy of from about 80 to about 150 calories per cc, preferably 100 to 115 calories/cc. The film is water resistant, unusually stable to UV radiation, nonirritating, and physically protective.
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