132338-12-6Relevant articles and documents
Treatment of multi-drug resistant tumors with pyridyloxazole-2-ones
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, (2008/06/13)
This invention relates to pyridinyloxazole-2-ones which are useful in the treatment of multi-drug resistant tumors. The pyridinyloxazole-2-ones act to prevent drug resistance and thus allow conventional chemotherapeutic agents to kill tumor cells as if drug resistance were not present.
Prevention of glycoprotein enveloped virus infectivity by pyridinyloxazole-2-ones
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, (2008/06/13)
This invention relates to pyridinyloxazole-2-ones which are useful anti-enveloped virus agents by virtue of their ability to act as protein kinase C inhibitors. These derivatives are disclosed to be effective in treating enveloped virus infections including HIV infections and are thus useful in the treatment of AIDS and ARC.
Cardiotonic heterocyclic oxazolones
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, (2008/06/13)
Heterocyclic oxazolones enhance myocardial contractile force and cardiac function and are used as cardiotonics in the treatment of heart failure.