Efficient synthesis of α-(hydroxymethyl) ketones not available through aldol-type processes
An efficient synthesis of α-(hydroxymethyl) ketones from β-keto esters has been developed, which is experimentally simple, amenable to large scale production and provides products of high purity without resort to chromatography in most cases. The method is a useful alternative and complement to condensation processes.
Hitchcock,Perron,Martin,Albizati
p. 1059 - 1061
(2007/10/02)
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