Synthesis of Methyl or Aryl Sulfonyl Hydroxy Biphenyls Catalyzed by Monoelectronic Transfer and Related Compounds
Methyl or aryl sulfonyl hydroxy biphenyls could be electrosynthesized in liquid ammonia via a SRN1 reaction, from chlorophenyl sulfones and 2,6-ditertbutylphenoxide.Further transformations such as tertbutyl groups elimination, alkylation at the
The present invention relates to novel compounds that are useful in the treatment of metabolic disorders, particularly type II diabetes mellitus and related disorders, and also to the methods for the making and use of such compounds.