A number of 1,8-naphthyridines including 8-aza analogues of chloroquine and amodiaquine, and similar 1,8-naphthyridines with 2- and 7-methyl substituents have been prepared.These compounds showed minimal antimalarial activity in a preliminary in vivo screen against Plasmodium vinckei vinckei.
Barlin, Gordon B.,Tan, Weng-Lai
p. 1065 - 1073
(2007/10/02)
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