132794-01-5Relevant articles and documents
Rhodium-Catalyzed Asymmetric Transfer Hydrogenation/Dynamic Kinetic Resolution of 3-Benzylidene-Chromanones
Molina Betancourt, Ricardo,Phansavath, Phannarath,Ratovelomanana-Vidal, Virginie
supporting information, p. 1621 - 1625 (2021/03/08)
Straightforward access to enantiomerically enriched cis-3-benzyl-chromanols from (E)-3-benzylidene-chromanones was developed through Rh-catalyzed asymmetric transfer hydrogenation. This transformation allowed the reduction of both the CaC and CaO bonds and the formation of two stereocenters in high yields with excellent levels of diastereo- A nd enantioselectivities (up to >99:1 dr, up to >99% ee) in a single step through a dynamic kinetic resolution process using a low catalyst loading and HCO2H/DABCO as the hydrogen source.
Homoisoflavonoids: Natural scaffolds with potent and selective monoamine oxidase-B inhibition properties
Desideri, Nicoletta,Bolasco, Adriana,Fioravanti, Rossella,Proietti Monaco, Luca,Orallo, Francisco,Yá?ez, Matilde,Ortuso, Francesco,Alcaro, Stefano
experimental part, p. 2155 - 2164 (2011/05/14)
A series of homoisoflavonoids [(E)-3-benzylidenechroman-4-ones 1a-w, 3-benzyl-4H-chromen-4-ones 2a-g, and 3-benzylchroman-4-ones 3a-e] have been synthesized and tested in vitro as inhibitors of human monoamine oxidase isoforms A and B (hMAO-A and hMAO-B).
