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133032-61-8

2(1H)-Quinolinone,7-(bromomethyl)-1-methyl-(9CI) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 133032-61-8 Structure

  • Basic information

    1. Product Name: 2(1H)-Quinolinone,7-(bromomethyl)-1-methyl-(9CI)
    2. Synonyms: 2(1H)-Quinolinone,7-(bromomethyl)-1-methyl-(9CI);7-(bromomethyl)-1-methylquinolin-2-one
    3. CAS NO:133032-61-8
    4. Molecular Formula: C11H10BrNO
    5. Molecular Weight: 252.1072
    6. EINECS: N/A
    7. Product Categories: QUINOLINONE
    8. Mol File: 133032-61-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2(1H)-Quinolinone,7-(bromomethyl)-1-methyl-(9CI)(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2(1H)-Quinolinone,7-(bromomethyl)-1-methyl-(9CI)(133032-61-8)
    11. EPA Substance Registry System: 2(1H)-Quinolinone,7-(bromomethyl)-1-methyl-(9CI)(133032-61-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 133032-61-8(Hazardous Substances Data)

133032-61-8 Usage

Structure

A quinolinone ring with a bromomethyl group attached to the 7th position and a methyl group attached to the 1st position.

Appearance

White to off-white solid

Solubility

Insoluble in water, soluble in organic solvents

Uses

主要用于制药和农药的合成中作为中间体，也用于有机合成，是其他化合物生产的构建模块。

Safety

由于其潜在危害，需要小心处理并遵循适当的安全预防措施。

Check Digit Verification of cas no

The CAS Registry Mumber 133032-61-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,0,3 and 2 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 133032-61:
(8*1)+(7*3)+(6*3)+(5*0)+(4*3)+(3*2)+(2*6)+(1*1)=78
78 % 10 = 8
So 133032-61-8 is a valid CAS Registry Number.

133032-61-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-bromomethyl-1-methyl-2-oxo-1,2-dihydroquinoline

1.2 Other means of identification

Product number -
Other names 7-bromomethyl-1,2-dihydro-1-methylquinolin-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:133032-61-8 SDS

133032-61-8Relevant articles and documents

An evaluation of 3,4-methylenedioxy phenyl replacements in the aminopiperidine chromone class of MCHr1 antagonists

Iyengar, Rajesh R.,Lynch, John K.,Mulhern, Mathew M.,Judd, Andrew S.,Freeman, Jennifer C.,Gao, Ju,Souers, Andrew J.,Zhao, Gang,Wodka, Dariusz,Doug Falls,Brodjian, Sevan,Dayton, Brian D.,Reilly, Regina M.,Swanson, Sue,Su, Zhi,Martin, Ruth L.,Leitza, Sandra T.,Houseman, Kathryn A.,Diaz, Gilbert,Collins, Christine A.,Sham, Hing L.,Kym, Philip R.

, p. 874 - 878 (2007)

The optimization of potent MCHr1 antagonist 1 with respect to improving its in vitro profile by replacement of the 3,4-methylenedioxy phenyl (piperonyl) moiety led to the discovery of 19, a compound that showed excellent MCHr1 binding and functional potencies in addition to possessing superior hERG separation, CYP3A4 profile, and receptor cross-reactivity profiles.

DIHYDRONAPHTHYRIDINYL AND RELATED COMPOUNDS FOR USE IN TREATING OPHTHALMOLOGICAL DISORDERS

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Page/Page column 42; 59, (2010/11/18)

The invention provides methods of using dihydronaphthyridinyl and related compounds to treat ophthalmological disorders, such as, wet age-related macular degeneration, diabetic retinopathy, and high myopia. Pharmaceutical compositions and methods of synthesizing the dihydronaphthyridinyl and related compounds are provided

Carboxamide Compounds and Their Use

-

Page/Page column 26; 30-31, (2010/12/31)

Chemokine receptor antagonists, in particular, compounds of Formula (I-A) that act as antagonists of the chemokine CCR2 receptor, including pharmaceutical compositions and uses thereof to treat or prevent diseases associated with monocyte accumulation, lymphocyte accumulation or leukocyte accumulation are described herein.

CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR

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Page/Page column 54; 59; 64, (2009/07/17)

Chemokine receptor antagonists, in particular, compounds of Formula (I) that act as antagonists of the chemokine CCR2 receptor, including pharmaceutical compositions and uses thereof to treat or prevent diseases associated with monocyte accumulation, lymphocyte accumulation or leukocyte accumulation are described; wherein (B/A) is an optionally substituted fused aromatic or partially aromatic bicyclic ring containing at least one nitrogen atom.

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