- Synthesis, evaluation and incorporation into liposomes of 4-functionalised-2,5-diphenyloxazole derivatives for application in scintillation proximity assays
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The preparation of a series of 4-functionalised-2,5-diphenyloxazoles is described. The scintillating efficiency of each of these 'scintilipid' molecules has been evaluated in the presence of ionising radiation. Each 'scintilipid' has been assessed for the ability to assemble, with other lipids, into liposomes, under a variety of preparative conditions. Each liposomal preparation has been monitored for the ability to scintillate in the presence of ionising radiation. The optimal 'scintilipid', both in terms of effective liposomal formation and scintillation efficiency, has been determined.
- McCairn, Mark C.,Culliford, Steven J.,Kozlowski, Roland Z.,Sutherland, Andrew J.
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p. 2163 - 2166
(2007/10/03)
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- Synthesis and scintillating efficiencies of 4-functionalised-2,5-Diphenyloxazoles
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A series of 4-functionalised-2,5-diphenyloxazoles has been synthesised. Each member of the series has been assessed for the ability to scintillate in the presence of ionising radiation. The scintillation counting efficiency of each member of the series has been determined relative to 2,5-diphenyloxazole, a widely used scintillant molecule.
- Clapham, Bruce,Richards, Amanda J.,Wood, Michael L.,Sutherland, Andrew J.
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p. 9061 - 9064
(2007/10/03)
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