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4-BROMO-3-FLUORO-BENZAMIDINE is a chemical compound characterized by a benzene ring with a bromine atom at the 4 position and a fluorine atom at the 3 position, which is attached to an amidine group. 4-BROMO-3-FLUORO-BENZAMIDINE is recognized for its potential as a building block in the synthesis of pharmaceuticals and agrochemicals, and it is valued for its ability to act as a potent inhibitor for various enzymes, making it a significant player in drug discovery and development processes. The unique combination of bromine and fluorine atoms in its structure contributes to its utility in medicinal chemistry for the creation of new drugs with enhanced pharmacokinetic properties. Furthermore, it has attracted interest for its role in cross-coupling reactions and as a precursor for a variety of molecular scaffolds.

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  • 133302-62-2 Structure
  • Basic information

    1. Product Name: 4-BROMO-3-FLUORO-BENZAMIDINE
    2. Synonyms: 4-BROMO-3-FLUORO-BENZAMIDINE;4-BROMO-3-FLUORO-BENZAMIDINE HYDROCHLORIDE;4-BroMo-3-fluorobenziMidaMide;4-Bromo-3-fluorobenzimidamide hydrochloride
    3. CAS NO:133302-62-2
    4. Molecular Formula: C7H6BrFN2*Cl*H
    5. Molecular Weight: 217.04
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 133302-62-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-BROMO-3-FLUORO-BENZAMIDINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-BROMO-3-FLUORO-BENZAMIDINE(133302-62-2)
    11. EPA Substance Registry System: 4-BROMO-3-FLUORO-BENZAMIDINE(133302-62-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 133302-62-2(Hazardous Substances Data)

133302-62-2 Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
4-BROMO-3-FLUORO-BENZAMIDINE is used as a building block for the synthesis of various pharmaceuticals and agrochemicals due to its ability to be incorporated into complex molecular structures, enhancing the development of new and effective compounds.
Used in Drug Discovery and Development:
4-BROMO-3-FLUORO-BENZAMIDINE is utilized as a potent enzyme inhibitor, playing a crucial role in the identification and development of new drugs targeting specific biological pathways.
Used in Medicinal Chemistry:
4-BROMO-3-FLUORO-BENZAMIDINE is employed in medicinal chemistry for the development of drugs with improved pharmacokinetic properties, capitalizing on the presence of both bromine and fluorine atoms to modulate the compound's activity and stability.
Used in Cross-Coupling Reactions:
4-BROMO-3-FLUORO-BENZAMIDINE is used as a reactant in cross-coupling reactions, a significant process in organic chemistry that allows for the formation of carbon-carbon bonds, leading to the creation of diverse molecular scaffolds.
Used as a Precursor for Molecular Scaffolds:
In the synthesis of complex organic molecules, 4-BROMO-3-FLUORO-BENZAMIDINE serves as a precursor, providing a foundation for the construction of a wide array of molecular scaffolds that can be further functionalized for specific applications in various chemical and biological fields.

Check Digit Verification of cas no

The CAS Registry Mumber 133302-62-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,3,0 and 2 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 133302-62:
(8*1)+(7*3)+(6*3)+(5*3)+(4*0)+(3*2)+(2*6)+(1*2)=82
82 % 10 = 2
So 133302-62-2 is a valid CAS Registry Number.

133302-62-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-bromo-3-fluorobenzenecarboximidamide,hydrochloride

1.2 Other means of identification

Product number -
Other names 4-bromo-3-fluorobenzenecarboximidamide hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:133302-62-2 SDS

133302-62-2Downstream Products

133302-62-2Relevant articles and documents

Pyrimidine derivatives and liquid crystal compositions including same

-

, (2008/06/13)

2-phenyl-5-(4'-trans-cyclohexyl) phenyl pyrimidine derivatives represented by the general formula: STR1 wherein R is a straight chain alkyl group having 1 to 10 carbon atoms; X is CN or F; Y is F or H; Z is F or H; and when X is F, at least one of Y and Z is H; and the cyclohexane ring is a trans isomer, exhibiting a nematic phase and having a high nematic phase-isotropic liquid phase transition temperature (N-I Point) and large positive dielectric constant anisotropy (Δε). The pyrimidine derivatives may be included in liquid crystal compositions for improved display devices having a wide temperature range, including a high N-I point, a low threshold voltage and a low driving voltage.

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