Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
Novel compounds of Formula (7.0a), (7.0b) or (7.0c): STR1 are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of the formula (7.0a), (7.0b) or (7.0c) to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.
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(2008/06/13)
Chemical Properties
Melting Point: 120-122°C
Boiling Point: 466.859°C at 760 mmHg
Flash Point:236.148°C
Density: 1.409g/cm3
Solubility:Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly), Methanol (Ve
