Synthesis and antimicrobial screening of pyrazolines and benzothiazepines incorporated with thiophene
Chalcones were synthesized by a base catalyzed Claisen-Schmidt condensation reaction. Chalcones were treated with hydrazine hydrate in ethanol to afford pyrazolihe derivatives. 1,5-Benzothiazepines have been synthesized from the reaction of chalcones and 2-aminothiophenol in ethanol at reflux conditions. The synthesized compounds were evaluated for their antimicrobial and antifungal activity against Gram +ve and Gram-ve microorganisms. Some of the compounds showed moderate activity.
Bhagat,Ghotekar,Badadhe,Chavan,Dixit,Gill
p. 355 - 358
(2013/09/24)
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