Synthesis and Antiviral Activity of Deoxy Analogs of 1--6-(phenylthio)thymine (HEPT) as Potent and Selective Anti-HIV-1 Agents
The effect of substitution in the acyclic structure of 1--6-(phenylthio)thymine (HEPT) on anti-HIV-1 activity was investigated by synthesizing a series of deoxy analogs and related compounds.Preparation of 1-(2-alkyloxyethoxy)met