The present invention provides novel diarylurea derivatives (compounds of formula (I)) and their uses. The compounds of the present invention are demonstrated to be allosteric modulators of the CB1 receptor, and therefore useful for the treatment of diseases and conditions mediated by CB1.
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Paragraph 69; 176; 234
(2018/12/02)
Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea
Tuberculosis is a major threat for mankind and the emergence of resistance strain of Mycobacterium tuberculosis (Mtb) against first line antibiotics makes it lethal for human civilization. In this study, we have synthesized different diaryl urea derivativ
Velappan, Anand Babu,Charan Raja, Mamilla R.,Datta, Dhrubajyoti,Tsai, Yi Ting,Halloum, Iman,Wan, Baojie,Kremer, Laurent,Gramajo, Hugo,Franzblau, Scott G.,Kar Mahapatra, Santanu,Debnath, Joy
supporting information
p. 825 - 841
(2016/10/25)
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