Enantioselective synthesis of chelidonine, a B/C-cis-11- hydroxyhexahydrobenzo[c]phenanthridine alkaloid
Both enantiomers of chelidonine, a B/C-cis-11-hydroxyhexahydrobenzo[c] phenanthridine alkaloid, were synthesized by manipulation of the B/C-dehydro ring juncture of benzo[c]phenanthridine skeleton using Sharpless asymmetric dihydroxylation and stereospecific catalytic hydrogenation after introduction of oxygen functions on the C ring as key reaction steps for the construction of stereogenic centers.
Get Best Price for1337985-33-7(-)-12-(3-chlorobenzoyloxy)-11-hydroxy-5-methyl-2,3:7,8-bis(methylenedioxy)-10b-triethylsilyloxy-4b,5,6,10b,11,12-hexahydrobenzo[c]phenanthridin-6(5H)-one