133943-59-6

Basic information

• Product Name: H-LEU-ARG-PRO-OH
• Synonyms: LHRH (7-9) SEQUENCE 2HCL;H-LEU-ARG-PRO-OH;H-LEU-ARG-PRO-OH 2HCL;LHRH 7-9 SEQUENCE;Leu-Arg-Pro;LRP;Leucylarginylproline
• CAS NO: 133943-59-6
• Molecular Formula: C17H32N6O4
• Molecular Weight: 384.47
• Mol File: 133943-59-6.mol

Chemical Properties

• Appearance: /
• Density: 1.39±0.1 g/cm3(Predicted)
• Storage Temp.: -15°C
• PKA: 3.39±0.20(Predicted)
• CAS DataBase Reference: H-LEU-ARG-PRO-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-LEU-ARG-PRO-OH(133943-59-6)
• EPA Substance Registry System: H-LEU-ARG-PRO-OH(133943-59-6)

Safety Data

• Hazardous Substances Data: 133943-59-6(Hazardous Substances Data)

Usage

Uses

Used in Biochemical Research:
H-LEU-ARG-PRO-OH is utilized as a research compound for investigating its potential biological activities and interactions with other molecules. Its specific amino acid sequence may provide insights into the structure and function of larger peptide chains and proteins.
Used in Pharmaceutical Development:
H-LEU-ARG-PRO-OH is employed as a potential therapeutic agent, given its possible biological activities. Its amino acid sequence could be explored for the development of new drugs, particularly in the context of peptide-based therapies.
Used in Nutritional Supplements:
H-LEU-ARG-PRO-OH may be incorporated into nutritional supplements as a source of essential amino acids, particularly for individuals with specific dietary requirements or those seeking to enhance their protein intake.
Used in Cosmetics and Personal Care Products:
H-LEU-ARG-PRO-OH could be used in the formulation of cosmetics and personal care products, leveraging its amino acid composition to provide skin-nourishing and rejuvenating benefits. Its potential biological activities may contribute to the development of innovative skincare and beauty products.

Upstream product

• 35661-60-0 Fmoc-Leu-OH 
• 71989-31-6 Fmoc-Pro-OH 
• 91000-69-0 Fmoc-L-Arg-OH 

Relevant articles and documents

Microencapsulation and modification of synthetic peptides of food proteins reduces the blood pressure of spontaneously hypertensive rats

Synthetic peptides were microencapsulated into liposomes, cycled with a disulfide bond or modified with D-phenylglycine (D-phg) at the N-terminal, and their antihypertensive effects as orally administered (0.18 mM/kg body weight) to spontaneously hypertensive rats (SHR) were measured. The microencapsulated Leu-Lys-Pro reduced significantly the systolic blood pressures of SHR by 45 mmHg and showed a prolonged duration, revealing the significant protective effect of encapsulation. D-phg-Leu-Arg-Pro showed a duration about 2 h shorter than that of the peptide without modification. In addition, cyclic Leu-Arg-Pro peptide with a disulfide bond between the N- and C-terminal amino acids reduced the systolic blood pressure of SHR by 35 mmHg and displayed a lengthy duration.