133978-59-3 Usage
Uses
Used in Pharmaceutical Industry:
2-(4-Amino-benzenesulfonylamino)-3-phenyl-propionic acid is used as a potential non-steroidal anti-inflammatory drug (NSAID) for its anti-inflammatory and analgesic properties. Its sulfonamide group contributes to its potential antibacterial and diuretic properties, while the phenyl group is commonly associated with NSAIDs. Further research is required to confirm its therapeutic potential and ensure its safety and efficacy for human use.
Check Digit Verification of cas no
The CAS Registry Mumber 133978-59-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,9,7 and 8 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 133978-59:
(8*1)+(7*3)+(6*3)+(5*9)+(4*7)+(3*8)+(2*5)+(1*9)=163
163 % 10 = 3
So 133978-59-3 is a valid CAS Registry Number.
InChI:InChI=1/C15H16N2O4S/c16-12-6-8-13(9-7-12)22(20,21)17-14(15(18)19)10-11-4-2-1-3-5-11/h1-9,14,17H,10,16H2,(H,18,19)/p-1/t14-/m1/s1
133978-59-3Relevant articles and documents
Design and synthesis of potent hydroxamate inhibitors with increased selectivity within the gelatinase family
Zapico, Jos Mara,Puckowska, Anna,Filipiak, Kamila,Coderch, Claire,De Pascual-Teresa, Beatriz,Ramos, Ana
, p. 142 - 156 (2015/02/05)
MMP-2 is a validated target for the development of anticancer agents. Herein we describe the synthesis of a new series of potent phenylalanine derived hydroxamates, with increased MMP-2/MMP-9 selectivity compared to analogous hydroxamates described previously. Docking and molecular dynamics experiments have been used to account for this selectivity, and to clarify the role of the triazole ring in the binding process. This journal is
