Synthesis of imidazo[4,5-c]quinolin-4(5H)-one via radical cyclization
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Suzuki,Kuroda
p. 811 - 813
(2007/10/02)
New bronchodilators. II. 3H-imidazo[4,5-c]quinolin-4(5H)-ones
A series of novel 3-substituted imidazo[4,5-c]quinolin-4(5H)-ones (2a-w) was prepared by the reaction of imidazo[4,5-c]quinolin-4(5H)-ones (6) with several electrophiles under basic conditions. The bronchodilatory activity of these compounds was evaluated
Novel imidazoquinolone derivative represented by formula (I); STR1 wherein R1 represents lower alkyl or --(CH2)m CO--R3 where R3 represents hydrogen, lower alkyl, hydroxy or lower alkoxy; and m is an integer of 1 to 3; R2 represents lower alkyl; or a pharmaceutically acceptable salt thereof.
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(2008/06/13)
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