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Ethyl 2-amino-4,5,6,7-tetrahydrobenzo[d]thiazole-6-carboxylate is a chemical compound belonging to the benzo[d]thiazole family, characterized by its ethyl ester functional group. With a molecular formula of C12H16N2O2S, ethyl 2-amino-4,5,6,7-tetrahydrobenzo[d]thiazole-6-carboxylate exhibits significant biological activities, such as antimicrobial and anticancer properties, making it a promising candidate for pharmaceutical applications.

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  • 134136-00-8 Structure
  • Basic information

    1. Product Name: ethyl 2-amino-4,5,6,7-tetrahydrobenzo[d]thiazole-6-carboxylate
    2. Synonyms: ethyl 2-amino-4,5,6,7-tetrahydrobenzo[d]thiazole-6-carboxylate;2-Amino-4,5,6,7-tetrahydrobenzothiazole-6-carboxylic acid ethyl ester
    3. CAS NO:134136-00-8
    4. Molecular Formula: C10H14N2O2S
    5. Molecular Weight: 226.29536
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 134136-00-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 380.873°C at 760 mmHg
    3. Flash Point: 184.146°C
    4. Appearance: /
    5. Density: 1.29g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.592
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 5.40±0.40(Predicted)
    11. CAS DataBase Reference: ethyl 2-amino-4,5,6,7-tetrahydrobenzo[d]thiazole-6-carboxylate(CAS DataBase Reference)
    12. NIST Chemistry Reference: ethyl 2-amino-4,5,6,7-tetrahydrobenzo[d]thiazole-6-carboxylate(134136-00-8)
    13. EPA Substance Registry System: ethyl 2-amino-4,5,6,7-tetrahydrobenzo[d]thiazole-6-carboxylate(134136-00-8)
  • Safety Data

    1. Hazard Codes: Xn
    2. Statements: 22-36/37/38
    3. Safety Statements: 26
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 134136-00-8(Hazardous Substances Data)

134136-00-8 Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 2-amino-4,5,6,7-tetrahydrobenzo[d]thiazole-6-carboxylate is used as a building block in organic synthesis for the preparation of various pharmaceutical and biologically active molecules. Its unique structure and functional groups contribute to the development of new drugs and therapeutic agents.
Used in Antimicrobial Applications:
Ethyl 2-amino-4,5,6,7-tetrahydrobenzo[d]thiazole-6-carboxylate is used as an antimicrobial agent, exhibiting activity against a range of microorganisms. Its ability to inhibit microbial growth makes it a potential candidate for the development of new antimicrobial drugs and treatments.
Used in Anticancer Applications:
Ethyl 2-amino-4,5,6,7-tetrahydrobenzo[d]thiazole-6-carboxylate is used as an anticancer agent, showing potential in targeting and inhibiting the growth of cancer cells. Its biological activities may contribute to the development of novel cancer therapies and treatment strategies.
Used in Research and Development:
Ethyl 2-amino-4,5,6,7-tetrahydrobenzo[d]thiazole-6-carboxylate is used in research and development for the discovery and design of new drugs and therapeutic agents. Its unique properties and potential applications make it a valuable tool in the advancement of pharmaceutical sciences.

Check Digit Verification of cas no

The CAS Registry Mumber 134136-00-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,1,3 and 6 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 134136-00:
(8*1)+(7*3)+(6*4)+(5*1)+(4*3)+(3*6)+(2*0)+(1*0)=88
88 % 10 = 8
So 134136-00-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2O2S/c1-2-14-9(13)6-3-4-7-8(5-6)15-10(11)12-7/h6H,2-5H2,1H3,(H2,11,12)

134136-00-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 2-amino-4,5,6,7-tetrahydro-1,3-benzothiazole-6-carboxylate

1.2 Other means of identification

Product number -
Other names 2-amino-4,5,6,7-tetrahydrobenzothiazole-6-carboxylic acid ethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:134136-00-8 SDS

134136-00-8Downstream Products

134136-00-8Relevant articles and documents

FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS ROR GAMMA MODULATORS

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, (2015/07/16)

The present invention provides fused thiophene and thiazole derivatives of formula (I), which may be therapeutically useful, more particularly as RORγ modulators; in which R1, R2, R3, R4, R5, R6, R7, X1, X2, L, m, n and ring A have the meanings given in the specification, and pharmaceutically acceptable salts thereof that are useful in the treatment and prevention of diseases or disorders, in particular their use in disease(s) or disorder(s) where there is an advantage in modulating RORγ receptor. The present invention also provides preparation of the compounds and pharmaceutical formulations comprising at least one of the fused thiophene and thiazole derivatives of formula (I), together with a pharmaceutically acceptable carrier, diluent or excipient therefor.

ANTI-INFECTIVE COMPOUNDS

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, (2016/06/28)

The present invention relates to small molecule compounds having the general formula (I): wherein A is a moiety selected from the group consisting of formulae (A) to (K) and their use in the treatment of bacterial infections, in particular Tuberculosis.

BENZAMIDE COMPOUNDS AS GLUCOKINASE ACTIVATORS AND THEIR PHARMACEUTICAL APPLICATION

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, (2011/09/14)

Benzamide compounds of formula (I), their stereoisomers, tautomers, prodrugs, pharmaceutically acceptable salts, polymorphs, solvates and formulations thereof useful as Glucokinase activators or modulators are disclosed. The disclosure further relates to

INTERMEDIATES FOR THE PREPARATION OF PRAMIPEXOLE

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Page/Page column 17, (2010/02/14)

Intermediates useful for the preparation of pramipexole and the use thereof in such synthesis.

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