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CAS

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134287-58-4

3,9-dihydro-3-((1,3-dihydroxy-2-propoxy)methyl)-6-methyl-9-oxo-5H-imidazol(1,2-a)purine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 3,9-dihydro-3-((1,3-dihydroxy-2-propoxy)methyl)-6-methyl-9-oxo-5H-imidazol(1,2-a)purine

    Cas No: 134287-58-4

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  • 134287-58-4 Structure

  • Basic information

    1. Product Name: 3,9-dihydro-3-((1,3-dihydroxy-2-propoxy)methyl)-6-methyl-9-oxo-5H-imidazol(1,2-a)purine
    2. Synonyms: 3,9-dihydro-3-((1,3-dihydroxy-2-propoxy)methyl)-6-methyl-9-oxo-5H-imidazol(1,2-a)purine
    3. CAS NO:134287-58-4
    4. Molecular Formula: C12H15 N5 O4
    5. Molecular Weight: 293.28
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 134287-58-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 642.7°C at 760 mmHg
    3. Flash Point: 342.5°C
    4. Appearance: /
    5. Density: 1.69g/cm3
    6. Vapor Pressure: 2.14E-17mmHg at 25°C
    7. Refractive Index: 1.754
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 3,9-dihydro-3-((1,3-dihydroxy-2-propoxy)methyl)-6-methyl-9-oxo-5H-imidazol(1,2-a)purine(CAS DataBase Reference)
    11. NIST Chemistry Reference: 3,9-dihydro-3-((1,3-dihydroxy-2-propoxy)methyl)-6-methyl-9-oxo-5H-imidazol(1,2-a)purine(134287-58-4)
    12. EPA Substance Registry System: 3,9-dihydro-3-((1,3-dihydroxy-2-propoxy)methyl)-6-methyl-9-oxo-5H-imidazol(1,2-a)purine(134287-58-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 134287-58-4(Hazardous Substances Data)

134287-58-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 134287-58-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,2,8 and 7 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 134287-58:
(8*1)+(7*3)+(6*4)+(5*2)+(4*8)+(3*7)+(2*5)+(1*8)=134
134 % 10 = 4
So 134287-58-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H15N5O4/c1-7-2-17-11(20)9-10(15-12(17)14-7)16(5-13-9)6-21-8(3-18)4-19/h2,5,8,18-19H,3-4,6H2,1H3,(H,14,15)

134287-58-4Downstream Products

134287-58-4Relevant articles and documents

Synthesis and antiviral activity of 3-substituted derivatives of 3,9-dihydro-9-oxo-5H-imidazo[1,2-a]purines, tricyclic analogues of acyclovir and ganciclovir

Boryski,Golankiewicz,De Clercq

, p. 2380 - 2383 (2007/10/02)

9-[(2-Hydroxyethoxy)methyl]guanine (acyclovir, 1a) and 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine (DHPG, ganciclovir, 1b) were transformed to their respective tricyclic derivatives, 3-substituted 3,9-dihydro-9-oxo-5H-imidazo[1,2-a]purines 2b, 3a, and 3b. The 6-methyl-substituted compound 2b was obtained following reaction of 1b with bromoacetone. A two-step approach via 1-(2,2-diethoxyethyl) intermediates 4a,b was the most effective for the preparation of the derivatives unsubstituted in the appended ring (3a,b). The novel acyclonucleosides, in particular ganciclovir derivative 2b, proved markedly active against herpes simplex virus type 1 and 2, varicella-zoster virus, and cytomegalovirus.

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