Construction of highly functional quaternary carbon stereocenters via an organocatalytic tandem cyanation-allylic alkylation reaction
The first tertiary amine-catalyzed tandem cyanation-allyic alkylation (CAA) reaction of aldehydes, appropriate cyanide sources, and Morita-Baylis-Hillman (MBH) adducts has been developed, which provides a facile access to densely functionalized products c