- One pot synthesis of some new N-allyl and N-benzyl quinazolinones and their anti-inflammatory activity
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The simple and more reliable one-pot synthesis of some novel compounds of allyl/Benzyl quinazolinone (4aa-4bd) with good yields from readily available derivatives of anthranilic acid and benzoyl chloride was also reported. Interestingly, as compared to Di
- Sudula, Sudharshan Reddy,Jala, Ranjith,Siddoju, Kavitha,Ega, Jagadeesh Kumar
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- Water as a hydrogen source in palladium-catalyzed reduction and reductive amination of nitroarenes mediated by diboronic acid
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An unprecedented palladium-catalyzed chemoselective reduction and reductive amination of nitroarenes with water as a hydrogen source mediated by diboronic acid have been discovered. A series of aryl amines containing various reducible functional groups were obtained in good to excellent yields.
- Zhou, Yanmei,Zhou, Haifeng,Liu, Sensheng,Pi, Danwei,Shen, Guanshuo
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p. 3898 - 3904
(2017/06/13)
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- RETRACTED ARTICLE: Novel 2-aminobenzamides as potential orally active antithrombotic agents
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In an effort to develop potent antithrombotic agents, a series of novel 2-aminobenzamide derivatives were synthesized and screened for their in vivo antithrombotic activity. Among the 23 compounds tested, compound (8g) showed the most promising antithrombotic activity, which was comparable with clinically used aspirin or warfarin, but at variance with these standard drugs, 8g did not exhibit the increased bleeding time, suggesting its potential as a novel antithrombotic agent.
- Verma, Amit,Giridhar, Rajani,Kanhed, Ashish,Sinha, Anshuman,Modh, Pratik,Yadav, Mange R.
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supporting information
p. 32 - 36
(2013/03/13)
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- The N-Aryl aminocarbonyl ortho-substituent effect in Cu-catalyzed aryl amination and its application in the synthesis of 5-substituted 11-Oxo-dibenzodiazepines
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Double amination of ortho-substituted aryl bromides proceeded under mild conditions to afford 5-substituted 11-oxo-dibenzodiazepines, which revealed that there is a strong ortho-substituent effect caused by N-aryl aminocarbonyl groups during copper-cataly
- Diao, Xiaoqiong,Xu, Lanting,Zhu, Wei,Jiang, Yongwen,Wang, Haoyang,Guo, Yinlong,Ma, Dawei
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supporting information; experimental part
p. 6422 - 6425
(2012/02/03)
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