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2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]benzamide is a complex organic compound with a molecular formula of C18H13BrClN4O3. It is a derivative of benzamide, featuring a 2-amino group attached to the benzene ring, and a carbamoyl group linked to a 4-(5-bromopyrimidin-2-yl)oxy-3-chlorophenyl moiety. 2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide is characterized by the presence of a bromine atom at the 5-position of the pyrimidine ring and a chlorine atom at the 3-position of the phenyl group. The structure of this chemical is notable for its potential applications in medicinal chemistry, particularly as a building block for the development of new drugs or as a chemical probe in biological research. Its specific properties and reactivity are influenced by the presence of the halogen atoms and the heterocyclic pyrimidine ring, which can engage in various chemical interactions and may be relevant to its biological activity.

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  • 134742-26-0 Structure
  • Basic information

    1. Product Name: 2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide
    2. Synonyms: 2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide
    3. CAS NO:134742-26-0
    4. Molecular Formula: C18H13BrClN5O3
    5. Molecular Weight: 462.68
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 134742-26-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: °Cat760mmHg
    3. Flash Point: °C
    4. Appearance: /
    5. Density: 1.663g/cm3
    6. Refractive Index: 1.708
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide(134742-26-0)
    11. EPA Substance Registry System: 2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chloro-phenyl]carbamoyl]ben zamide(134742-26-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 134742-26-0(Hazardous Substances Data)

134742-26-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 134742-26-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,7,4 and 2 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 134742-26:
(8*1)+(7*3)+(6*4)+(5*7)+(4*4)+(3*2)+(2*2)+(1*6)=120
120 % 10 = 0
So 134742-26-0 is a valid CAS Registry Number.
InChI:InChI=1/C18H13BrClN5O3/c19-10-8-22-18(23-9-10)28-15-6-5-11(7-13(15)20)24-17(27)25-16(26)12-3-1-2-4-14(12)21/h1-9H,21H2,(H2,24,25,26,27)

134742-26-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chlorophenyl]carbamoyl]benzamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:134742-26-0 SDS

134742-26-0Relevant articles and documents

Synthesis and antitumor activities of water-soluble benzoylphenylureas

Okada, Hiroshi,Kato, Masanari,Koyanagi, Tohru,Mizuno, Kazuhiko

, p. 430 - 433 (2007/10/03)

Water-soluble benzoylphenylurea derivatives were synthesized as candidate prodrugs and their antitumor activities were examined in vivo against P388 leukemia. Some of the prodrugs were highly soluble in water and showed good antitumor activities against P388 leukemia cells in mice when injected intravenously.

Substituted benzoylurea compounds or their salts, processes for their production and antitumour compositions containing them

-

, (2008/06/13)

A substituted benzoylurea compound of the formula (I): STR1 wherein R1 is a hydrogen atom, a halogen atom or a nitro group, each of R2 and R3 is a hydrogen atom, an alkyl group, --COR6 (wherein R6 is an alkyl group or an alkoxy group) or --SO2 R6 (wherein R6 is as defined above), or R2 and R3 may form together with the adjacent nitrogen atom a heterocyclic ring, R4 is a halogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkoxy group, a substituted or unsubstituted alkylthio group or a nitro group, and R5 is a halogen atom, a nitro group or a substituted or unsubstituted alkyl group, or its salt.

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