A novel benzenesulfonamide derivative of formula (I) which has an action of inhibiting phospholipase A2? and therefore is effective in treating diseases for which this action is used to advantage.
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(2022/01/13)
Synthesis and biological evaluation of substituted benzenesulfonamides as novel potent membrane-bound phospholipase A2 inhibitors
A novel series of 4-[N-methyl-N-[(E)-3-[4-(methylsulfonyl)phenyl]-2-propenoyl]amino]benz enesulfonamides has been prepared and evaluated as membrane-bound phospholipase A2 inhibitors. A structure-activity relationship study indicated that the o