Synthesis and Functionalization of trans-2-(2'-Aminocyclohexyloxy)- and trans-2-(2'-Azidocyclohexyloxy)acetic Acid
Synthesis of the hydrochloride of trans-2-(2'-aminocyclohexyloxy)acetic acid (4) from trans-2-(2'-azidocyclohexyloxy)acetic acid (1) is described. 4 was acylated at the amino group to give compounds 5-8. 1 was converted into acid chloride (9) and amides 1