134984-99-9

Basic information

• Product Name: furaquinocin D
• Synonyms: furaquinocin D;(2R)-2,3-Dihydro-4-hydroxy-3α-[(R)-1-hydroxy-4-methyl-3-pentenyl]-7-methoxy-2α,3,8-trimethylnaphtho[1,2-b]furan-6,9-dione
• CAS NO: 134984-99-9
• Molecular Formula: C₂₂H₂₆O₆
• Molecular Weight: 386.44
• Mol File: 134984-99-9.mol

Chemical Properties

• Boiling Point: 611.4°Cat760mmHg
• Flash Point: 213.3°C
• Appearance: /
• Density: 1.28g/cm³
• Vapor Pressure: 8.37E-16mmHg at 25°C
• Refractive Index: 1.597
• PKA: 6.61±0.60(Predicted)
• CAS DataBase Reference: furaquinocin D(CAS DataBase Reference)
• NIST Chemistry Reference: furaquinocin D(134984-99-9)
• EPA Substance Registry System: furaquinocin D(134984-99-9)

Safety Data

• Hazardous Substances Data: 134984-99-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C22H26O6/c1-10(2)7-8-15(24)22(5)12(4)28-21-16-13(9-14(23)17(21)22)19(26)20(27-6)11(3)18(16)25/h7,9,12,15,23-24H,8H2,1-6H3

Upstream product

• 143893-02-1 (2R,3S)-4-Hydroxy-3-((Z)-(R)-1-hydroxy-4-methyl-5-phenylsulfanyl-pent-3-enyl)-7-methoxy-2,3,8-trimethyl-2,3-dihydro-naphtho[1,2-b]furan-6,9-dione 
• 217486-47-0 (2R,3S)-4-(tert-Butyl-dimethyl-silanyloxy)-3-((R)-1-hydroxy-4-methyl-pent-3-enyl)-7-methoxy-2,3,8-trimethyl-2,3-dihydro-naphtho[1,2-b]furan-6,9-dione 
• 217486-32-3 (2R,3R)-9-Benzyloxy-6,7-dimethoxy-4-(2-methoxy-ethoxymethoxy)-2,3,8-trimethyl-2,3-dihydro-naphtho[1,2-b]furan-3-carbaldehyde 
• 217486-38-9 (2R,3R)-9-Benzyloxy-6,7-dimethoxy-4-(2-methoxy-ethoxymethoxy)-2,3,8-trimethyl-3-(S)-oxiranyl-2,3-dihydro-naphtho[1,2-b]furan 
• 217486-76-5 (2R,3S)-4-(tert-Butyl-dimethyl-silanyloxy)-3-((R)-1-hydroxy-4-methyl-pent-3-enyl)-6,7-dimethoxy-2,3,8-trimethyl-2,3-dihydro-naphtho[1,2-b]furan-9-ol 
• 217486-75-4 (2R,3S)-9-Benzyloxy-3-((R)-1-hydroxy-4-methyl-pent-3-enyl)-6,7-dimethoxy-2,3,8-trimethyl-2,3-dihydro-naphtho[1,2-b]furan-4-ol 
• 217486-62-9 [(2R,3S)-9-Benzyloxy-6,7-dimethoxy-4-(2-methoxy-ethoxymethoxy)-2,3,8-trimethyl-2,3-dihydro-naphtho[1,2-b]furan-3-ylmethoxy]-tert-butyl-dimethyl-silane 
• 125108-66-9 furaquinocin A 
• 217486-29-8 Acetic acid (2R,3S)-9-benzyloxy-3-(tert-butyl-dimethyl-silanyloxymethyl)-6,7-dimethoxy-2,3,8-trimethyl-2,3-dihydro-naphtho[1,2-b]furan-4-yl ester 
• 217486-45-8 (R)-1-[(2R,3S)-9-Benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-6,7-dimethoxy-2,3,8-trimethyl-2,3-dihydro-naphtho[1,2-b]furan-3-yl]-4-methyl-pent-3-en-1-ol 
• 217486-67-4 [(2R,3S)-9-Benzyloxy-6,7-dimethoxy-4-(2-methoxy-ethoxymethoxy)-2,3,8-trimethyl-2,3-dihydro-naphtho[1,2-b]furan-3-yl]-methanol 
• 217486-42-5 (R)-1-[(2R,3S)-9-Benzyloxy-6,7-dimethoxy-4-(2-methoxy-ethoxymethoxy)-2,3,8-trimethyl-2,3-dihydro-naphtho[1,2-b]furan-3-yl]-4-methyl-pent-3-en-1-ol 

Relevant articles and documents

Total synthesis of the furaquinocins

A viable synthetic route to the furaquinocin-class antibiotics is described. The key steps include (1) Co-complex mediated stereospecific 1,2- shift of an alkynyl group (9 → 6) to establish the c(2)-C(3) stereochemical relationship, (2) efficient construc

FURAQUINOCINS A-G: RELATIVE AND ABSOLUTE STEREOCHEMISTRY

The complete relative and absolute stereochemistry of furaquinocins A-G, a family of cytotoxic anibiotics, have been assigned via a combination of X-ray crystallography, NMR analysis of the derived Mosher esters, and chemical correlation.