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1-Bromo-cyclopropanecarbonitrile, also known as bromocyclopropane carbonitrile, is a chemical compound characterized by its molecular formula C4H4BrN. It is a colorless to pale yellow liquid that is recognized for its high reactivity due to the presence of both bromine and nitrile functional groups. 1-Bromo-cyclopropanecarbonitrile is a significant entity in the field of organic synthesis and pharmaceutical research, primarily utilized for the preparation of various pharmaceuticals and agrochemicals.

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  • 1350746-42-7 Structure
  • Basic information

    1. Product Name: 1-Bromo-cyclopropanecarbonitrile
    2. Synonyms: 1-Bromo-cyclopropanecarbonitrile
    3. CAS NO:1350746-42-7
    4. Molecular Formula: C4H4BrN
    5. Molecular Weight: 145.98526
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1350746-42-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 190.0±23.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.75±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-Bromo-cyclopropanecarbonitrile(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-Bromo-cyclopropanecarbonitrile(1350746-42-7)
    11. EPA Substance Registry System: 1-Bromo-cyclopropanecarbonitrile(1350746-42-7)
  • Safety Data

    1. Hazard Codes: Xn
    2. Statements: 36/37/38
    3. Safety Statements: 26-37
    4. WGK Germany:
    5. RTECS:
    6. TSCA: No
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 1350746-42-7(Hazardous Substances Data)

1350746-42-7 Usage

Uses

Used in Organic Synthesis:
1-Bromo-cyclopropanecarbonitrile is used as a reagent in organic synthesis for its ability to readily participate in chemical reactions, facilitating the creation of a wide range of organic molecules.
Used in Pharmaceutical Research:
In pharmaceutical research, 1-Bromo-cyclopropanecarbonitrile is employed as a key intermediate in the development of new drugs, leveraging its reactive nature to form complex molecular structures that can address specific medical needs.
Used in Agrochemicals:
1-Bromo-cyclopropanecarbonitrile is used as a precursor in the synthesis of agrochemicals, contributing to the development of compounds that can protect crops and enhance agricultural productivity.
Used in the Synthesis of Heterocyclic Compounds:
1-Bromo-cyclopropanecarbonitrile is also utilized in the synthesis of heterocyclic compounds, which are an important class of organic molecules with diverse applications in medicine, materials science, and other fields.
Precaution:
It is crucial to handle 1-Bromo-cyclopropanecarbonitrile with care due to its toxic nature and potential hazards to human health and the environment. Proper safety measures should be implemented during its use to mitigate any risks associated with its reactivity and toxicity.

Check Digit Verification of cas no

The CAS Registry Mumber 1350746-42-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,0,7,4 and 6 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1350746-42:
(9*1)+(8*3)+(7*5)+(6*0)+(5*7)+(4*4)+(3*6)+(2*4)+(1*2)=147
147 % 10 = 7
So 1350746-42-7 is a valid CAS Registry Number.

1350746-42-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-Bromocyclopropanecarbonitrile

1.2 Other means of identification

Product number -
Other names 1-Cyanocyclopropyl bromide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1350746-42-7 SDS

1350746-42-7Downstream Products

1350746-42-7Relevant articles and documents

A cyclopropyl armor cyanogen method for preparing derivatives of

-

Paragraph 0039; 0040, (2016/12/22)

The invention relates to a preparation method of a cyclopropyl methyl cyanide derivative with a general formula I. The preparation method is as below: first synthesizing cyclopropyl formonitrile by using cyclopropanecarboxamide as raw material, then synthesizing a halogenated butyronitrile derivative, and finally synthesizing the target product cyclopropyl methyl cyanide derivative. The invention provides a complete process route, and carefully investigates and researches raw materials and process conditions in each step, so that the method provided by the invention is more efficient and secure, and low in energy consumption and cost, and applicable to large-scale industrialized production.

An efficient synthesis of 1-bromo-1-cyanocyclopropane

Xue, Feng,Li, Chang-Gong,Zhu, Yong,Lou, Tian-Jun

, p. 418 - 419 (2014/08/05)

An efficient process for the synthesis of 1-bromo-1-cyanocyclopropane has been developed starting from inexpensive γ-butyrolactone via bromination, cyclisation, ammoniation and dehydration reaction. The sequence proceeds in good yield.

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