Pyridoxine-derived bicyclic aminopyridinol antioxidants: Synthesis and their antioxidant activities
A few facile synthetic pathways for bicyclic aminopyridinol antioxidants are presented. Attachment of a long alkyl chain to the bicyclic pyridinol scaffold was established using ester linkage. Non-substituted pyrrolopyridinols and 1,3-oxazine-fused pyridinols were also synthesized as novel antioxidant scaffolds. Antioxidant activities were measured by a radical clock method and new compounds prepared are comparable to the best bicyclic aminopyridinol antioxidants. The Royal Society of Chemistry 2011.
Nam, Tae-Gyu,Ku, Jin-Mo,Rector, Christopher L.,Choi, Hoyoung,Porter, Ned A.,Jeong, Byeong-Seon
experimental part
p. 8475 - 8482
(2012/04/04)
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