135242-93-2

Basic information

• Product Name: (1-Methyl-1H-[1,2,4]triazol-3-yl)-methanol
• Synonyms: (1-Methyl-1H-[1,2,4]triazol-3-yl)-methanol;1H-1,2,4-Triazole-3-methanol, 1-methyl-;1-methyl-1H-1,2,4-Triazole-3-methanol
• CAS NO: 135242-93-2
• Molecular Formula: C₄H₇N₃O
• Molecular Weight: 113.11788
• Mol File: 135242-93-2.mol

Chemical Properties

• Boiling Point: 296.847 °C at 760 mmHg
• Flash Point: 133.329 °C
• Appearance: /
• Density: 1.336 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 13.16±0.10(Predicted)
• CAS DataBase Reference: (1-Methyl-1H-[1,2,4]triazol-3-yl)-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1-Methyl-1H-[1,2,4]triazol-3-yl)-methanol(135242-93-2)
• EPA Substance Registry System: (1-Methyl-1H-[1,2,4]triazol-3-yl)-methanol(135242-93-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 135242-93-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(1-Methyl-1H-[1,2,4]triazol-3-yl)-methanol is used as a building block for the synthesis of various medications. Its unique chemical structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agricultural Processes:
(1-Methyl-1H-[1,2,4]triazol-3-yl)-methanol may also have applications in agriculture, potentially serving as a component in the formulation of agrochemicals or as a precursor in the synthesis of compounds that can enhance crop protection and yield.
Used in Industrial Processes:
In the industrial sector, (1-Methyl-1H-[1,2,4]triazol-3-yl)-methanol could be utilized in the production of a wide range of organic compounds, including those used in coatings, adhesives, and other chemical products, due to its reactivity and functional group diversity.
It is important to handle (1-Methyl-1H-[1,2,4]triazol-3-yl)-methanol with care, as it may possess hazardous properties. Proper safety protocols should be followed during its use to ensure the safety of individuals and the environment.

Upstream product

• 135206-74-5 3-tert-butyldimethylsilyloxymethyl-1-methyl-1H-1,2,4-triazole 
• 57031-66-0 methyl 1-methyl-1H-1,2,4-triazole-3-carboxylate 
• 60-34-4 methylhydrazine 

Downstream Products

• 135206-76-7 3-chloromethyl-1-methyl-1H-[1,2,4]triazole hydrochloride 
• 233278-54-1 1-methyl-1,2,4-triazol-3-ylmethyl chloride 
• 215871-44-6 (1-methyl-1H-1,2,4-triazol-3-yl)methanamine hydrochloride 
• 126748-87-6 1-methyl-1H-1,2,4-triazole-3-carbaldehyde 

Relevant articles and documents

Synthesis, Characterization, Antimicrobial Activity, and Docking Studies of New Triazolic Tripodal Ligands

The synthesis and characterization of new N-donor bitriazolic tripods were reported. The in?vitro antibacterial and antifungal activities of these products were screened against fungal strain (Candida pelliculosa) and against four bacterial strains (Micro

Optically active antifungal azoles. III. Synthesis and antifungal activity of sulfide and sulfonamide derivatives of (2R,3R)-2-(2,4-difluorophenyl)-3- mercapto-1-(1H-1,2,4-triazol-1-yl)-2-butanol

In an effort to find potent antifungal agents, optically active sulfur- containing triazole derivatives, sulfides (3) and sulfonamides (4), were prepared and evaluated for antifungal activity against Candida albicans in vitro and in vivo. The sulfides (3) were prepared by the reaction of (2R,3R)- 2-(2,4-difluorophenyl)-3-mercapto-1-(1H-1,2,4-triazol-1-yl)-2-butanol (1) with various heteroarylmethyl chlorides in the presence of sodium methoxide. The sulfonamides (4) were synthesized starting from the disulfide (15) in three steps including oxidation of the corresponding sulfenamides (17). Some of the sulfur-containing triazole derivatives (3, 4) showed strong protective effects against candidosis in mice.