New cholesterol esterase inhibitors based on rhodanine and thiazolidinedione scaffolds
We present a new class of inhibitors of pancreatic cholesterol esterase (CEase) based on 'priviledged' 5-benzylidenerhodanine and 5-benzylidene-2,4- thiazolidinedione structural scaffolds. The lead structures (5- benzylidenerhodanine 4a and 5-benzylidene-
Heng, Sabrina,Tieu, William,Hautmann, Stephanie,Kuan, Kevin,Pedersen, Daniel Sejer,Pietsch, Markus,Gütschow, Michael,Abell, Andrew D.
p. 7453 - 7463
(2012/01/06)
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