Method for preparing chiral compound by using intermediate
The invention provides a method for preparing a chiral compound by using an intermediate. The method is characterized by comprising the following steps: (a) enabling a compound II to be contacted witha compound III in a solvent, and refining to obtain a c
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Paragraph 0088-0090; 0094-0096
(2018/11/04)
PROCESS FOR THE PREPARATION OF A SINGLE ENANTIOMER OF 3-AMINOPIPERIDINE DIHYDROCHLORIDE
A process comprising: (a) reduction of N-acetyl-3-aminopyridine (2): or its salt in the presence of hydrogen and a palladium catalyst deposited on solid support; (b) converting racemic N-acetyl-3-aminopiperidine (3) or its salt produced in step (a) to rac-3-aminopiperidine (rac-4) or its salt; (c) resolution of the racemic 3-aminopiperidine (rac-4) or its salt produced in step (b) with a chiral acid.
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(2012/01/06)
METHOD FOR PRODUCING 3-AMINOPIPERIDINE DIASTEREOMER
A method for increasing the enantiomeric purity of a desired enantiomer of 3- aminopiperidine comprising: providing a composition containing (i?)-3-arninopiperidine and (jS)-3-aminopiperidine; combining the composition with a resolving agent selected from
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Page/Page column 4-5
(2008/06/13)
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